Magic Mushroom's Active Compound Could Relieve Depression For Up To One Year, New Study Finds

A new review study by Johns Hopkins University researchers is shedding light on the long-term effects of psilocybin in the treatment of major depression.

In a new study, 58% of participants with major depressive disorder were in remission after one year of doing two sessions with psilocybin.

“Psilocybin not only produces significant and immediate effects, it also has a long duration, which suggests that it may be a uniquely useful new treatment for depression,” said Roland Griffiths, Ph.D., Professor in Neuropsychopharmacology of Consciousness at Johns Hopkins School of Medicine.

Psilocybin, also known as the active compound in “magic mushrooms,” is one of the compounds spearheading a pipeline that looks to advance psychedelic drugs for medical use.

 

The Sustained Long-Term Results Of Psilocybin Against Depression

Johns Hopkins University has been leading academic research into psilocybin for the past decade. In earlier studies, researchers found that psychedelic-assisted psychotherapy treatment with psilocybin relieved symptoms of depression in adults for up to a month.

“Compared to standard antidepressants, which must be taken for long stretches of time, psilocybin has the potential to enduringly relieve the symptoms of depression with one or two treatments,” continued Griffiths.

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